Spironolactone can be prescribed for androgenic alopecia in women. This is a type of hair loss that’s associated with the overproduction of male sex hormones. Spironolactone slows down the production of androgens. These are male sex hormones, including testosterone. Reduced production of androgens can slow down the progression of hair loss caused by androgenic alopecia. It can also encourage hair to regrow.
Finasteride (Proscar and Propecia) was originally developed to treat enlarged prostate glands. Propecia is the first drug in history to effectively treat male pattern baldness in the majority of men who use it. Finasteride’s hair-raising success is due to its ability to specifically inhibit 5-alpha-reductase, the enzyme that converts testosterone into a more potent androgen dihydrotestosterone (DHT). It is DHT that shrinks or miniaturizes the hair follicle, which eventually leads to baldness.